A database of hormones and their receptors |
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HMRbase accession number | 10350 |
Swiss-prot Accession number | Q9DD49 (Sequence in FASTA format) |
Description | Progonadoliberin-3 precursor (Progonadoliberin III) (Salmon-typegonadotropin-releasing hormone) (sGnRH) [Contains: Gonadoliberin-3(Gonadoliberin III) (Luteinizing hormone-releasing hormone III) (LH-RHIII) (Gonadotropin-releasing hormone III) (GnRH III) (Luliberin III);GnRH-associated peptide 3 (GnRH-associated peptide III)]. |
Source organism | Oryzias latipes (Medaka fish) (Japanese ricefish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Atherinomorpha;Beloniformes; Adrianichthyidae; Oryziinae; Oryzias. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | Expressed in neuron cell bodies of the nucleus olfactoretinalis |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 90 Amino acids |
Molecular weight | 10176 |
References | 1 PubMed abstract 11006121 2 PubMed abstract 12137956 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-3 |
Mature Hormone Sequence | QHWSYGWLPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (24-33) |
Receptor | Q76KC7 Detail in HMRbase Q76L92 Detail in HMRbase Q76L93 Detail in HMRbase Q90VY1 Detail in HMRbase Q90W00 Detail in HMRbase |
Gene ID | 100049220 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 11509 |
Swiss-prot Accession number | Q9DGC8 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) (Medaka-typegonadotropin-releasing hormone) (mdGnRH) (mfGnRH) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
Source organism | Oryzias latipes (Medaka fish) (Japanese ricefish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Atherinomorpha;Beloniformes; Adrianichthyidae; Oryziinae; Oryzias. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | Expressed in the cell bodies of a cluster of neurons in the preoptic region |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 91 Amino acids |
Molecular weight | 10307 |
References | 1 PubMed abstract 11006121 2 PubMed abstract 12137956 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSFGLSPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (22-31) |
Receptor | Q76KC7 Detail in HMRbase Q76L92 Detail in HMRbase Q76L93 Detail in HMRbase Q90VY1 Detail in HMRbase Q90W00 Detail in HMRbase |
Gene ID | 100049266 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 11510 |
Swiss-prot Accession number | Q9DGC9 (Sequence in FASTA format) |
Description | Progonadoliberin-2 precursor (Progonadoliberin II) (Chicken-type IIgonadotropin-releasing hormone) (cGnRH-II) [Contains: Gonadoliberin-2(Gonadoliberin II) (Luteinizing hormone-releasing hormone II) (LH-RHII) (Gonadotropin-releasing hormone II) (GnRH II) (Luliberin II);GnRH-associated peptide 2 (GnRH-associated peptide II)]. |
Source organism | Oryzias latipes (Medaka fish) (Japanese ricefish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Atherinomorpha;Beloniformes; Adrianichthyidae; Oryziinae; Oryzias. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | Expressed in the cell bodies of a cluster of neurons in the midbrain tegmentum |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 80 Amino acids |
Molecular weight | 9311 |
References | 1 PubMed abstract 11006121 2 PubMed abstract 12137956 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-2 |
Mature Hormone Sequence | QHWSHGWYPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (22-31) |
Receptor | Q76KC7 Detail in HMRbase Q76L92 Detail in HMRbase Q76L93 Detail in HMRbase Q90VY1 Detail in HMRbase Q90W00 Detail in HMRbase |
Gene ID | 100049219 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 11534 |
Swiss-prot Accession number | Q588F9 (Sequence in FASTA format) |
Description | Leptin; Precursor |
Source organism | Oryzias latipes (Medaka fish) (Japanese ricefish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Atherinomorpha;Beloniformes; Adrianichthyidae; Oryziinae; Oryzias. |
Subcellular location | Secreted (Probable) |
Developmental Stage | N/A |
Similarity | Belongs to the leptin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | May function as part of a signaling pathway that acts to regulate the size of the body fat depot (By similarity). |
Protein Length | 155 Amino acids |
Molecular weight | 17291 |
References | 1 PubMed abstract 15808904 |
Domain Name | N/A |
Hormone Name | Leptin |
Mature Hormone Sequence | |
Position of mature hormone in Pre-Hormone protein | |
Receptor | N/A |
Gene ID | 100049298 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |